As a child, Lindstrand was interested in drawing. He had studied commercial art and worked in commercial illustration before beginning his career at the glass manufacturer Orrefors in 1928. In 1950 he joined Kosta Glasbruk as an artistic director before his retirement in 1973. At Kosta, he was the dominant designer, lending his name to many now classic designs. At this point, Lindstrand began to inject more and more colour into his creations, which resulted in iconic designs such as Trees in the Fog and Autumn. He spent the last 10 years of his life as a freelance artist working with Hanne Dreutler and Arthur Zirrnsack at Studio Glashyttan in Åhus.
He made his debut as a designer at the Stockholm World Fair in 1930, where he presented twelve glass vases with enamel decor in exotic patterns. For this he received great attention from international design publications. Lindstrand added new artistic dimensions to the already famous Orrefors glass with his unique designs and revitalization of classic forms and techniques. During his time at Orrefors he worked on engraved glass and Graal vases. With sculptor Edvin Öhrström he developed the new Ariel technique (named by his actress wife Kristina). Orrefors could not afford to keep Lindstrand during the war and between 1943 and 1950 he became creative leader at Uppsala Ekeby, where he designed many different stoneware objects ranging from pots to figural sculptures.